09/2000-01/2005: Ph.D., Materials Science and Engineering, Tsinghua University, P.R. China 09/1996-07/2000: B.S., Materials Science and Engineering, Tsinghua University, P.R. China
12/2013-present: Professor, School of Materials Science and Engineering, Tsinghua University, P.R. China 01/2009-12/2013: Associate Professor, Department of Materials Science and Engineering, Tsinghua University, P.R. China 01/2008-12/2008: Assistant Professor, Department of Materials Science and Engineering, Tsinghua University, P.R. China 06/2006-01/2008: Postdoctoral Associate, Center for Biomedical Engineering, Massachusetts Institute of Technology, U.S.A 07/2005-06/2006: Postdoctoral Fellow, Center for Musculoskeletal Research, University of Rochester, U.S.A
Tissue engineering and Regenerative medicine: Designing and fabricating biomaterials presented bioactive chemical, physical, and biological cues to control cell fate especially for tissue engineering and regenerative medicine. Angiogenesis Nerve tissue Regeneration Bone tissue engineering
The State Natural Science Award (Second Class, No. 2011-Z-108-2-03, the second achiever), the State Council of the P.R. China, 2011. (The first class award is vacant.) Chinese Medical Science and Technology Awards (Third Class, 201103069U0201, the fourth achiever), the Ministry of Health and the Ministry of Science and Technology of the P.R. China, 2011. Beijing Science and Technology Award (Second Class, No. 2010Cai-2-004, the Second achiever), Beijing City, 2010. Shandong Science and Technology Progress Award (First Class, No. JB2014-1-19-R04, the fourth achiever), Shandong Province, 2015. Selected in Program for New Century Excellent Talents in University of Ministry of Education of China, 2013 2012 Young Scholar of Distinction of Tsinghua University
1.Zhang ZX, Yao SL, Xie S*, Wang XM*, Chang FY, Luo J, Wang JM, Fu J. Effect of hierarchically aligned fibrin hydrogel in regeneration of spinal cord injury demonstrated by tractography: A pilot study. Scientific Report. Scientific Reports, 2017, 7, 40017. 2.Yao SL, Liu X, Yu SK, Wang XM*, et al. Co-effects of matrix low elasticity and aligned topography on stem cell neurogenic differentiation and rapid neurite outgrowth. Nanoscale, 2016, 8, 10252-10265. 3.Xu SJ, Qiu ZY, Wu JJ, Kong XD, Weng XS, Cui FZ*, Wang XM*. Osteogenic Differentiation Gene Expression Profiling of hMSCs on Hydroxyapatite and Mineralized Collagen. Tissue Engineering Part A. 2016; 22: 170-181. 4.Guan FY, Lu JJ, Wang XM*. A novel honeycomb cell assay kit designed for evaluating horizontal cell migration in response to functionalized self-assembling peptide hydrogels. Frontiers of Materials Science. 2017, 11(1):13-21. 5.Liu FZ, Wang DW, Zhang YJ, Lv ZY, Sun XD, Li KY, Zhang B*, Wang XM*, Cui FZ. Comparison of rabbit rib defect regeneration with and without graft. Journal of Materials Science-Materials in Medicine. 2017, 28(1): 10.1007/s10856-016-5807-1. 6.Liu FZ, Lv ZY, Zhang YJ, Li KY, Wang DW, Zhang B*, Wang XM*. Comparison of Rabbit Rib Defect Regeneration Implanted Mineralized Collagen With and Without Periosteum. Journal of Biomaterials and Tissue Engineering. 2017, 7(2): 134-138. 7.Yao SL, Liu X, He J, Wang XM*, Wang Y, and Cui FZ. Ordered self-assembled monolayers terminated with different chemical functional groups direct neural stem cell linage behaviours. Biomedical Materials. 2016, 11(1): 014107. 8.Zhou JF, Cheng L, Sun XD*, Wang XM*, Jin SH, Li JX, Wu Q. Neurogenic differentiation of human umbilical cord mesenchymal stem cells on aligned electrospun polypyrrole/polylactide composite nanofibers with electrical stimulation. Frontiers of Materials Science. 2016, 10(3): 260-269. 9.Meng QY, Tao CS, Qiu ZY, Akaike T, Cui FZ, Wang XM*. A hybrid substratum for primary hepatocyte culture that enhances hepatic functionality with low serum dependency. International Journal of Nanomedicine. 2015: 10, 2313-2323. 10.Qiu ZY, Cui Y, Tao CS, Zhang ZQ, Tang PF, Mao KY, Wang XM*, Cui FZ. Mineralized Collagen: Rationale, Current Status, and Clinical Applications. Materials 2015, 8(8), 4733-4750. 11.Liu X, Pi B, Wang H, Wang XM*. Self-assembling peptide nanofiber hydrogels for central nervous system regeneration. Frontiers of Materials Science. 2015, 9(1): 1-13. 12.Lian XJ*, Mao KZ, Liu X, Wang XM, and Cui FZ. In Vivo Osteogenesis of Vancomycin Loaded Nano-Hydroxyapatite /Collagen/ Calcium Sulfate Composite for Treating Infectious Bone Defect Induced by Chronic Osteomyelitis. Journal of Nanomaterials. 2015. 261492. 13.Tao H, Wu YH, Li HF, Wang CF, Zhang Y, Li C, Wen TY, Wang XM, et al. BMP7-Based Functionalized Self-Assembling Peptides for Nucleus Pulposus Tissue Engineering. ACS Applied Materials & Interfaces. 2015. 7(31): 17076-17087. 14.Wang RH, Wang Q, Wang XM*, et al. Enhancement of nano-hydroxyapatite bonding to dentin through a collagen/calcium dual-affinitive peptide for dentinal tubule occlusion. Journal of Biomaterials Applications. 2014. 29 (2): 268-277. 15.Tao H, Zhang Y, Wang C, Zhang C, Wang XM, et al. Biological evaluation of human degenerated nucleus pulposus cells in functionalized self-assembling peptide nanofiber hydrogel scaffold. Tissue Eng Part A. 2014. 20(11-12): 1621-1631. 16.Xiao YY, Zhang WZ, Wang XM*, et al. Optimized Preparation of Thiolated Hyaluronic Acid Hydrogel with Controllable Degree of Substitution. Journal of Biomaterials and Tissue Engineering. 2014. 4(4): 281-287. 17.Meng QY, Yao SL, Wang XM*, Chen YY. RADA16: a self-assembly peptide hydrogel for the application in tissue regeneration. Journal of Biomaterials and Tissue Engineering. 2014, 4(12): 1019-1029. 18.Liu X, Wang XM*, Wang XJ, et al. Functionalized self-assembling peptide nanofiber hydrogels mimic stem cell niche to control human adipose stem cells behaviors in vitro. Acta Biomaterialia. 2013, 9, 6798-6805. 19.Yao SL, Wang XM*, Liu X, et al. Effects of ambient relative humidity and solvent properties on the electrospinning of pure hyaluronic acid nanofibers. Journal of nanoscience and nanotechnology. 2013. 13: 4752-4758. 20.Yao SL, Liu X, Wang XM*, et al. Directing neural stem cell fate with biomaterial parameters for injured brain regeneration. Progress in Natural Science: Materials International. 2013, 23(2), 103-112. 21.Liu X, He J, Zhang SM, Wang XM*, Liu HY, and Cui FZ. The fate of adipose stem cells controlled by surface chemistry. Journal of Tissue Engineering and Regen Med. 2013, 7(2): 112-117. 22.Lian XJ, Liu HY, Wang XM*, et al. Antibacterial and biocompatible properties of vancomycin-loaded nano-hydroxyapatite/collagen/poly (lactic acid) bone substitute (VCM/nHAC/PLA). Progress in Natural Science-Materials International. 2013. 23(6): 549-556. 23.Liu X, Wang XM*, Horii A, Wang XJ, Qiao L, Zhang SG, and Cui FZ. In vivo studies on angiogenic activity of two designer self-assembling peptide scaffold hydrogels in the chicken embryo chorioallantoic membrane. Nanoscale. 2012, 4 (8), 2720-2727. 24.Wang XM*, He J, Wang Y, and Cui FZ. Hyaluronic acid-based scaffold for central neural tissue engineering. Interface Focus. 2012, 2, 278-291. 25.Deng H#, Wang XM#, Du C, et al. Combined effect of ion concentration and functional groups on the surface chemistry modulated CaCO3 crystallization. CrystEngComm. 2012, 14, 6647-6653. 26.Liu ZX#, Wang XM#, Wang Q, et al. Evolution of calcium phosphate crystallization on three functional group surfaces with the same surface density. CrystEngComm. 2012, 14, 6695-6701. 27.He J, Wang XM*, Sepctor M, and Cui FZ. Scaffolds for central nervous system regeneration. Frontiers of Materials Science. 2012, 6(1): 1-25. 28.Wang Q, Wang XM*, Tian LL, Cheng ZJ, and Cui FZ. In situ remineralization of partially demineralized human dentine mediated by a biomimetic non-collagen peptide. Soft Matter. 2011, 7, 9673-9680. 29.Wang XM*, Qiao L, and Horii A. Screening of functionalized self-assembling peptide nanofiber scaffolds with angiogenic activity for endothelial cell growth. Progress in Natural Science: Materials International. 2011, 21, 111-116. 30.Chen ZJ, Wang Q, Wang XM*, Cui FZ, Ge J, Chen D, and Tian LL. Enamel Distribution, Structure and Mechanical Alterations in col1-caPPR Mice Molar. Archives of Oral Biology. 2011, 56, 1020-1026.
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